Synthorx has a total of 392 patents globally, out of which 70 have been granted. Of these 392 patents, more than 96% patents are active. United States of America is where Synthorx has filed the maximum number of patents, followed by Japan and Taiwan. Parallelly, USA seems to be the main focused R&D centre and also is the origin country of Synthorx.
Synthorx founded in 2014, Synthorx is a biotechnology company developing therapies for cancer and autoimmune disorders. Using its proprietary Expanded Genetic Alphabet platform, the company engineers optimized biologics called Synthorins by incorporating novel amino acids into proteins. Its lead candidate, THOR-707 (a variant of IL-2), is being developed for multiple tumor types both as a standalone therapy and in combination with immune checkpoint inhibitors.
Do read about some of the most popular patents of Synthorx which have been covered by us in this article and also you can find Synthorx patents information, the worldwide patent filing activity and its patent filing trend over the years, and many other stats over Synthorx patent portfolio.
How many patents does Synthorx have?
Synthorx has a total of 392 patents globally. These patents belong to 22 unique patent families. Out of 392 patents, 357 patents are active.
How Many Patents did Synthorx File Every Year?

Are you wondering why there is a drop in patent filing for the last two years? It is because a patent application can take up to 18 months to get published. Certainly, it doesn’t suggest a decrease in the patent filing.
| Year of Patents Filing or Grant | Synthorx Applications Filed | Synthorx Patents Granted |
| 2025 | 3 | 28 |
| 2024 | 15 | 25 |
| 2023 | 31 | 11 |
| 2022 | 41 | 4 |
| 2021 | 65 | 1 |
| 2020 | 129 | 1 |
| 2019 | 45 | – |
| 2018 | 61 | – |
| 2016 | 2 | – |
How many Synthorx patents are Alive/Dead?
Worldwide Patents

How Many Patents did Synthorx File in Different Countries?

Countries in which Synthorx Filed Patents
| Country | Patents |
| United States of America | 35 |
| Japan | 24 |
| Taiwan | 22 |
| Europe (EPO) | 21 |
| Australia | 20 |
| Singapore | 20 |
| New Zealand | 18 |
| Korea (South) | 18 |
| Israel | 17 |
| Mexico | 17 |
| Hong Kong (S.A.R.) | 15 |
| Canada | 15 |
| Brazil | 14 |
| China | 14 |
| South Africa | 14 |
| Indonesia | 11 |
| Malaysia | 11 |
| India | 11 |
| Argentina | 9 |
| Viet Nam | 8 |
| Colombia | 8 |
| Philippines | 8 |
| Russia | 7 |
| Thailand | 2 |
| Saudi Arabia | 2 |
| Morocco | 2 |
| Spain | 1 |
| Italy | 1 |
| Germany | 1 |
Where are Research Centres of Synthorx Patents Located?
The Research Centre for all the Synthorx patents is the United States of America.
10 Best Synthorx Patents
WO2019028419A1 is the most popular patent in the Synthorx portfolio. It has received 165 citations so far from companies like Pandion Therapeutics, Cytune Pharma and Synthekine.
Below is the list of 10 most cited patents of Synthorx:
| Publication Number | Citation Count |
| WO2019028419A1 | 165 |
| WO2019028425A1 | 77 |
| WO2019014267A1 | 68 |
| US20200181220A1 | 57 |
| WO2019165453A1 | 35 |
| US10610571B2 | 29 |
| WO2020163532A1 | 27 |
| US20170369871A1 | 25 |
| WO2021133839A1 | 23 |
| WO2021030706A1 | 19 |
What Percentage of Synthorx US Patent Applications were Granted?
Synthorx (Excluding its subsidiaries) has filed 32 patent applications at USPTO so far (Excluding Design and PCT applications). Out of these 6 have been granted leading to a grant rate of 54.55%.
Below are the key stats of Synthorx patent prosecution at the USPTO.

Which Law Firms are managing US Patents for Synthorx?
| Law Firm | Total Applications | Success Rate |
| Mcneill Pllc | 27 | 81.25% |
| Merck Fox Rothschild Llp | 3 | 0% |
| Wilson Sonsini Goodrich & Rosati | 2 | 0.00% |
What are Synthorx key innovation segments?
What Technologies are Covered by Synthorx?

The chart below distributes patents filed by Synthorx in different countries on the basis of the technology protected in patents. It also represents the markets where Synthorx thinks it’s important to protect particular technological inventions.

R&D Focus: How has Synthorx search focus changed over the years?

EXCLUSIVE INSIGHTS COMING SOON!
Interested in knowing about the areas of innovation that are being protected by Synthorx?