Nuvalent has a total of 188 patents globally, out of which 19 have been granted. Of these 188 patents, 93.6% patents are active. United States of America is where Nuvalent has filed the maximum number of patents, followed by Japan and Korea (South). Parallelly, United States of America seems to be the main focused R&D centre and also is the origin country of Nuvalent.
Founded in 2017, Nuvalent is a clinical-stage biopharmaceutical company focused on discovering, developing, and commercializing precisely targeted therapies for patients with cancer. Leveraging deep expertise in chemistry and structure-based drug design, the company develops innovative small-molecule kinase inhibitors designed to overcome treatment resistance, improve selectivity, and address brain metastases associated with clinically proven cancer targets.
Nuvalent’s pipeline includes investigational therapies for ROS1-positive, ALK-positive, and HER2-altered non-small cell lung cancer (NSCLC), along with additional discovery-stage oncology programs. The company is committed to advancing next-generation targeted therapies that deliver more durable clinical responses and improve outcomes for patients with difficult-to-treat cancers
In July 2026, GSK completed the acquisition of Nuvalent for approximately $10.6 billion to strengthen its oncology portfolio. The acquisition expands GSK’s pipeline with Nuvalent’s clinical-stage precision oncology therapies, including late-stage targeted treatments for ROS1-positive and ALK-positive non-small cell lung cancer (NSCLC), as well as an early-stage HER2-directed program. This transaction supports GSK’s strategy to accelerate the development of next-generation targeted cancer therapies and address significant unmet needs in precision oncology.
Do read about some of the most notable patents of Nuvalent covered in this article. You can also explore Nuvalent’ patent portfolio, worldwide patent filing activity, patent filing trends over the years, and many other statistics related to its patent portfolio.
How many patents does Nuvalent have?
Nuvalent has a total of 188 patents globally. These patents belong to 14 unique patent families. Out of 188 patents, 176 patents are active.
How Many Patents did Nuvalent File Every Year?
Are you wondering why there is a drop in patent filing for the last two years? It is because a patent application can take up to 18 months to get published. Certainly, it doesn’t suggest a decrease in the patent filing.
| Year of Patents Filing or Grant | Nuvalent Applications Filed | Nuvalent Patents Granted |
| 2026 | 3 | 5 |
| 2025 | 9 | 5 |
| 2024 | 21 | 7 |
| 2023 | 52 | 2 |
| 2022 | 63 | – |
| 2021 | 40 | – |
How many Nuvalent patents are Alive/Dead?
Worldwide Patents
How Many Patents did Nuvalent File in Different Countries?
Top Countries in which Nuvalent Filed Patents
| Country | Patent |
| United States of America | 14 |
| Japan | 13 |
| Korea (South) | 11 |
| New Zealand | 10 |
| Europe (EPO) | 9 |
| China | 9 |
| Hong Kong (S.A.R.) | 8 |
| Australia | 8 |
| Israel | 8 |
| Singapore | 8 |
| Mexico | 8 |
| Canada | 8 |
| South Africa | 8 |
| Malaysia | 7 |
| Eurasia | 7 |
| Brazil | 7 |
| Philippines | 7 |
| Indonesia | 6 |
| India | 6 |
| Chile | 3 |
| Viet Nam | 3 |
| Peru | 3 |
| Taiwan | 3 |
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Where are Research Centres of Nuvalent Patents Located?
10 Best Nuvalent Patents
WO2021226269A1 is the most popular patent in the Nuvalent portfolio. It has received 21 citations so far from companies like Companies, Innovo Therapeutics, and Syngenta Crop Protection Ag.
Below is the list of 10 most cited patents of Nuvalent:
| Publication Number | Citation Count |
| WO2021226269A1 | 21 |
| WO2023056405A1 | 9 |
| WO2023056431A1 | 8 |
| US11542278B1 | 6 |
| US11667649B2 | 4 |
| WO2024086634A1 | 3 |
| US12037346B2 | 2 |
| CN115916196A | 2 |
| WO2025072117A1 | 2 |
| WO2025072120A1 | 2 |
What Percentage of Nuvalent US Patent Applications Were Granted?
Nuvalent (Excluding its subsidiaries) has filed 11 patent applications at USPTO so far (Excluding Design and PCT applications). Out of these 5 have been granted leading to a grant rate of 100%.
Below are the key stats of Nuvalent patent prosecution at the USPTO.
Which Law Firms are managing US Patents for Nuvalent?
| Law Firm | Total Applications | Success Rate |
| Jones Day | 11 | 100.0% |
What are Nuvalent key innovation segments?
What Technologies are Covered by Nuvalent?
The chart below distributes patents filed by Nuvalent