This Ranking has been awarded considering the Filing Year of the Total patents filed by the Inventors from Illinois state of the US, ranging from year 2011 to 2021. We have taken into account the addresses of Inventors from Illinois obtained from the patent applications data sourced from USPTO database.
| SR No | Inventors | Count of Patents | Affiliations |
| 1 | Jason K. Resch | 1021 | Alwaysasking.Com | Global Communications Network Llc | International Business Machines | Cleversafe Inc |
| 2 | Gary W. Grube | 426 | Caerus Institute | Motorola |
| 3 | Austin Grant Walters | 596 | Vizient Inc | Elevance Health | Unitedhealth Group | Viverae | Steele Consulting Llc |
| 4 | Vijay Nangia | 332 | Motorola Mobility Inc |
| 5 | Ravi Kuchibhotla | 295 | Motorola |
| 6 | Rachid Mohsen Alameh | 244 | – |
| 7 | Yufei Blankenship | 258 | Ericsson | Huawei | Motorola Mobile Devices |
| 8 | Brian Fields | 221 | State Farm |
| 9 | Kurt Wilcox | 191 | Cree Lighting | Cree |
| 10 | Michael R. Vogler | 217 | Thermoflex Corporation | Suncast Corporation |
| 11 | Reza Farivar | 280 | Twilio | Research And Engineering Frontier Labs | University Of Illinois At Urbana-Champaign | Capital One | Yahoo |
| 12 | Philippe Sartori | 136 | Samsung Electronics | Futurewei Technologies | Motorola Labs | Motorola Corporate Research |
| 13 | Jacob Alt | 114 | – |
| 14 | Chad A. Mirkin | 97 | Northwestern Univesity |
| 15 | Robert T. Love | 156 | Robert T Love | Motorola Mobility | E-Systems | Texas Instruments |
| 16 | Taghi Abad Fardin Abdi | 307 | Tubi | Capital One | Ceb | Bosch North America |
| 17 | Christopher P. Nicholas | 124 | Lakril Technologies | C2P Sciences L3C | Paschall & Associates Llc | Honeywell Uop | Sigma Aldrich |
| 18 | Ravi V. Khadiwala | 175 | – |
| 19 | Shawn M. Call | 125 | – |
| 20 | Kyungyoon Min | 129 | – |
| 21 | Hossein Bagheri | 135 | Motorola Mobility | Huawei | University Of Alberta | University Of Waterloo |
| 22 | Leon Oliver Stenneth | 234 | – |
| 23 | Steven C. Cielocha | 150 | Abbott |
| 24 | Yigang Cai | 168 | Freelance | Nokia Bell Labs | Nokia | Alcatel-Lucent Usa Inc. | Lucent Technologies Bell Labs Innovations | At&T Bell Laboratories | Argonne National Laboratory | Zhejiang University |
| 25 | Michael Thuma | 185 | – |
| 26 | Alakananda Bhattacharyya | 176 | – |
| 27 | William J. Leise | 123 | – |
| 28 | Jialing Liu | 99 | Futurewei Technologies | Motorola | Garmin International |
| 29 | Mark B. Gagner | 149 | – |
| 30 | Jaime Skaggs | 93 | State Farm |
| 31 | Kristopher Keith Gaudin | 109 | Movinx | Gaudin Ventures Llc | American Family Insurance | State Farm |
| 32 | Thomas D. Wetsch | 110 | Pregis | Insight Promotions Llc | Alcoa |
| 33 | Antonio Facchetti | 85 | Northwestern University | Polyera Corporation |
| 34 | Scott Farris | 117 | – |
| 35 | Aaron Scott Chan | 149 | – |
| 36 | Thomas L. Floyd | 133 | – |
| 37 | Qiang Cheng | 26 | – |
| 38 | Donald E. Weder | 148 | – |
| 39 | Amr Abdelmonem | 145 | Isco International |
| 40 | Stanley Joseph Frey | 85 | – |
| 41 | Andrew J. Souers | 93 | Abbvie | Abbott |
| 42 | Paul Michael Lesley | 124 | Red Circle Design Inc | Scientific Games | Wms Gaming | Nypro |
| 43 | Kenneth F. Stensrud | 51 | – |
| 44 | Marvin Lane | 121 | – |
| 45 | Mario Rosario Carlone | 129 | Dupont Pioneer | Garst Seed Compan |
| 46 | Eric Bellas | 75 | State Farm | Systems Analyst |
| 47 | Nathan L. Tofte | 131 | – |
| 48 | Todd Binion | 120 | State Farm |
| 49 | Michael J. Burns | 135 | Burns Consulting Services Llc | Tradingtechnologies International | Exchange Connectivity |
| 50 | Jason J. Stoller | 73 | Precision Planting Agco Corporation | Precision Planting Monsanto | Caterpillar Inc |
| 51 | Larry J. Pacey | 135 | – |
| 52 | Murali Narasimha | 114 | – |
| 53 | Kent E. Regnier | 98 | Molex |
| 54 | Donald Kyle | 116 | – |
| 55 | Vicki King | 76 | Apria Healthcare | State Farm |
| 56 | Joel Jaffe | 109 | Zenith Electronics | Bell And Howell | Wms Gaming |
| 57 | Andrew Guinn | 101 | – |
| 58 | Blake Konrardy | 119 | Hiroad | Kin Insurance | Stats Llc | Sportio | State Farm | Supplemental Brewing | Sole Owner |
| 59 | William P. Alberth | 42 | – |
| 60 | Brian Classon | 127 | Futurewei Technologies Inc. | Huawei | Motorola |
| 61 | Debabrata Pal | 134 | Collins Aerospace | Utc Aerospace Systems | Motorola |
| 62 | Dale M. Koch | 74 | – |
| 63 | Vipul Desai | 83 | Futurewei Technologies | Motorola |
| 64 | Mark C. Hersam | 70 | – |
| 65 | Paul A. Bertin | 67 | Grove Biopharma Inc | Elevance Renewable Sciences | Ohmx Corporation |
| 66 | Chunqing Liu | 88 | Honeywell | University Of Illinois Urbana | Northwestern University |
| 67 | Gerald Horn | 90 | Lenz Therapeutics | Breinfuel | Lasikplus (Lca-Vision Inc.) | Eye Therapies | Preferred Solution Therapies | Ocuphire Pharma |
| 68 | Jayant Kumar Gorawara | 57 | – |
| 69 | Ajit Nimbalker | 173 | – |
| 70 | Richard B. Silverman | 78 | – |
| 71 | Scott F. Singer | 118 | Artisan Partners | Wedge Capital Managemen | Wellington Management | Raymond James |
| 72 | Dwayne Boroski | 117 | Thermos L.L.C. |
| 73 | Melinda T. Magerkurth | 65 | Country Financia | State Farm | Safeco Insurance | Liberty Mutual Insurance | Normal Cornbelters |
| 74 | George Calcev | 74 | Futurewei Technologies | Motorola Labs | Control Department University Politechnica Bucharest | |
| 75 | Jiri Slaby | 85 | – |
| 76 | Jamie W. Vann | 43 | Everi Holdings Inc | Strawdog Theatre | Cientific Games – Wms |
| 77 | Glenn C. Lemmers | 118 | – |
| 78 | Jackie O. Jordan | 93 | – |
| 79 | Jeremy M. Hornik | 45 | – |
| 80 | Timothy C. Loose | 76 | Self-Employed | Scientific Games | Perkinelmer Las | Wms Gaming | Sonoscan |
| 81 | Paolo Palmas | 76 | – |
| 82 | Deng-Yang Jan | 77 | – |
| 83 | John W. Labuszewski | 103 | – |
| 84 | Bussche Kurt M. Vanden | 53 | – |
| 85 | Michael Dragonuk | 97 | – |
| 86 | Frederick W. Masanek | 101 | – |
| 87 | Masud Bolouri-Saransar | 72 | – |
| 88 | Kenneth Taylor | 113 | – |
| 89 | Michael J. Schuster | 73 | Red Door Coffee | 111 Minna Gallery | Blazing Saddles Bike Rentals And Tours | Target | Burke Warren Mackay & Serritella |
| 90 | Robert L. Bedard | 48 | Uop Llc – A Honeywell |
| 91 | Damon E. Gura | 64 | – |
| 92 | Khalil Amine | 94 | Argonne National Laboratory |
| 93 | Gregory I. Rozman | 110 | Avne | Wpg Americas Inc | Techni-Tool | Rohde & Schwarz | Anadigics |
| 94 | Ethan S. Wozniak | 91 | Ocient | Ibm | Government Accountability Office |
| 95 | Xin X. Zhu | 65 | Honeywell Uop | University Of Manchester |
| 96 | Larry W. Kiest | 90 | Lmk Pipe Renewal | Lmk Technologies Llc |
| 97 | Martin D. Burke | 41 | Revolution Medicines |
| 98 | Todd Swanson | 28 | – |
| 99 | Gavin P. Towler | 40 | Honeywell Performance Materials And Technologies | Uop | Umist |
| 100 | Christopher C. Winslade | 98 | Mcandrews Held & Malloy Ltd |